We typically see robotic arms being used in welding or pick-and-place applications on production lines. This class will cover some lesser-known uses that are becoming more relevant in manufacturing, with a focus on subtractive machining. Though not as commonly used as traditional computer numerical control (CNC) machines, they offer versatility by enabling attachment of various end effectors, such as CNC tool spindles, additive extruders, and even grinders or polishers. They can therefore be used as subtractive, additive, and postprocessing machines. The PowerMill Robot plug-in takes advantage of PowerMill software’s innovative 3- and 5-axis toolpaths and the toolpath editing features to apply them to a wide range of supported robots. We will primarily cover subtractive manufacturing in both industrial and artistic settings. Attendees will learn the workflow, from setting up a robot cell, calculating toolpaths, and optimizing robot motion for efficiency and safety.